Immune Gene Expression against Similar Damselfish Virus (SRDV) Induced by Immunization with Inactivated Vaccine in Juvenile Koi Carp

Viral diseases are one of the major challenges that are threatening a sustainable growth of fish farming and wild populations globally. Fish viral diseases account for large-scale mortality in farmed fish and are very difficult to treat directly. In the last decade, ranaviruses have been identified as responsible agents for causing disease outbreaks mainly in hatchery reared larvae and juveniles of a wide variety of fishes throughout the world (Whittington et al., 2010). Ranaviruses are associated with numerous disease outbreaks in natural and cultured populations of fish, amphibians and reptiles (Chinchar, 2002; Chinchar et al., 2009). Several ranavirus isolates have been recovered from different host species in Australia, the Americas, Europe and Asia (Williams et al., 2005). Ranaviruses belong to one of the five genera of the family Iridoviridae (Jancovich et al., 2011). They are large icosahedral, double-stranded DNA International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 6 Number 9 (2017) pp. 1391-1402 Journal homepage: http://www.ijcmas.com